Q.pruning muscadine grape vines
Our grape vine is SERIOUSLY overgrown. Can I cut at least part of it back this month?
Thank you.

Grapes are ideally pruned every winter, because that way you will avoid removing leaves that are still actively providing energy for the plant. You can remove some of the overgrowth now, but keep this to a minimum and remove the rest of the overgrowth after the vine has lost all its leaves. Here's more about how to prune grapevines:
https://www.gardeningknowhow.com/edible/fruits/grapes/prune-grape-vine.htm
http://extension.oregonstate.edu/gardening/node/642
http://articles.extension.org/pages/31140/pruning-grape-vines:-an-overview