What can I do to prepare and protect the plant from periods of freezing temperatures?
Certified GKH Gardening Expert
If you are in zones 7 and up, it will require no extra care. If you are outside of this range then the best method is to bring it inside. Here is an article for more information: https://www.gardeningknowhow.com/ornamental/flowers/ligularia/leopard-plant-care.htm