Q.trees
Why do cottonwood trees sap from some branches?

Downtoearthdigs
Answered on October 24, 2016
It sounds like your Cottonwood Tree is infected with Bacterial Wetwood or Slime Flux disease.
Here are some links that have more information for you.
https://extension.psu.edu/pests/plant-diseases/all-fact-sheets/wetwood-or-slime-flux
https://www.gardeningknowhow.com/ornamental/trees/tgen/wetwood-bleeding-trees.htm
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