I've started growing Glycyrrhizin Glabra and Glycyrrhizin Echinata and am planning to cross pollinate them. Will it work? Also I've briefly heard on the internet, that Licorice leaves are not edible, but I can't find any information on the internet, as to why. Would the leaves have the same or similar health benefits as the root? For example I've heard that Licorice root is anti-aging, would the leaves have the same effect?
Glycyrrhiza glabra is the cultivated licorice plant grown for its sweet roots. Echinata is a wild form so you are crossing a cultivated variety with a wild variety. You can try crossing them. If they aren't a viable match, the new plant won't grow.
Apparently, licorice leaves do not contain glycyrrhizin, the sweetener that is in the roots. If the roots are harvested for the anti-aging benefit, the leaves must not contain the desirable agent. Not all parts, i.e., roots, stems, leaves, flowers, of all plants offer the same benefits.
https://www.gardeningknowhow.com/edible/herbs/licorice/growing-licorice-plants.htm
https://extension.unl.edu/statewide/cass/Pollination%20Basics%20June%202019.docx.pdf
I've heard that you shouldn't harvest it after a year, because it might not be able to survive the harvest. But I'm growing multiple Liquorice plants, so maybe I could harvest some after a year and leave the rest to continue growing.
When you harvest the roots, you can replant some or part of the rhizomes to get more plants going.
The extract is toxic in large doses, and the toxic property is removed before using in products commercially. So, I am concerned as to how you are going to use the root. Here is more on its care and toxicity.
https://plants.ces.ncsu.edu/plants/glycyrrhiza-glabra/
https://www.gardeningknowhow.com/edible/herbs/licorice/growing-licorice-plants.htm
I have heard that Liquorice has anti-aging effects, good for itchiness and is good for anxiety. I drink it as a tea and it has been helping me. I have been growing liquorice, hopefully in a year or a few years I'll have enough liquorice root to consume from what I'm growing, for the time being I buy the liquorice root.
I couldn't find any information on smoking licorice root, other than its use to flavor tobacco products. I did find several reports of the dangers of consuming too much licorice root, which you may find of interest. The FDA also warns of not consuming a lot of black licorice over a short period of time. I suggest speaking to your doctor before smoking any licorice root.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582380/
https://blogs.ifas.ufl.edu/nassauco/2017/05/28/fact-sheet-licorice/
https://www.wtamu.edu/~cbaird/sq/2013/09/03/does-licorice-cause-high-blood-pressure/
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=19&contentid=Licorice
Here is information on growing licorice plants:
https://www.gardeningknowhow.com/edible/herbs/licorice/growing-licorice-plants.htm