What's your question? Ask

You can try a general purpose fungicide or go with a fungicide containing ferbam.

There are several diseases that can infect holly as well as other shrubs, so perhaps your soil is infected with one of those. For example, in the following list,
phytophthora root rot and Thielaviopsis root rot can attack both hollies and other shrubs:
http://extension.psu.edu/pests/plant-diseases/all-fact-sheets/holly-diseases
https://www.ces.ncsu.edu/depts/pp/notes/oldnotes/od13.htm
http://extension.psu.edu/pests/plant-diseases/all-fact-sheets/thielaviopsis-or-black-root-rot

http://ipm.illinois.edu/diseases/series600/rpd641/

Another possibility is environmental issues, such as a pH problem or high salt concentration in that area of your soil.

It's probably best to have an extension agent or arborist look at the shrubs you have in that spot and try to diagnose what the problem is. That way you'll be able to take the appropriate control measures to correct whatever is causing the disease.

Deer resistant does not mean that the plants are immune to deer attacks and that deer will not eat the plants. The plants may leave a bad taste or the leaves may cut them. If deer are sufficiently hungry, they may eat just about anything. Try applying Plantskydd; it does not have to be reapplied after it rains. Eventually, the deer that visited may learn that the hollies are not such a good source of food and it will nibble elsewhere. A "new" visitor, though, may have to learn that the hard way so spraying may deter causing damage too.

These roots will send adventitious shoots out on occasion. They will seek any area that is suitable for them to send a shoot, and gaps in concrete are perfect for this.

Sealing those areas off, and maintaining some of the cracks will eliminate most of this, outside of hand-pulling and chemical control.

The good news is that these are not very destructive, however they are taking advantage of a place to send a shoot. Being a Chinese Holly, these will be more prolific than our own native types.

https://www.gardeningknowhow.com/ornamental/trees/tgen/problem-tree-roots.htm

There could be several possibilities, but it would be hard to say for certain, as your photos did not come through. I could guess snails or slugs, though. It can be hard to spot them since they feed at night. There could be many culprits, though.

The spots could be some disease caused by the creature eating it. You may need to treat the area with a fungicide to keep this from spreading.