I have 2 small spider plants in a small pot. When I replant to a larger pot, should I separate them?
This is entirely a personal choice on your part as the plants would thrive as 2 or separated.
Often times people separate the plants to share with other gardeners!
Make sure you do not use to large of a pot. Usually when repotting you only need to go up 1 or 2 sizes larger.
Spider plants actually prefer to be root bound.
Here is a link that should help you.