Rose leaves have got holes in them and white splashes on them.
Sounds like you could have both a bug or worm problem and perhaps powdery mildew. Spraying the rosebushes with a product called Green Cure will handle the powdery mildew. Inspect the underside of the rose leaves and see if you find the culprits hiding there. They may also only be visible at night with a flashlight as many such pests like to emerge and feed by the cool of the evening. Then spray with an insecticide of choice as needed.