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While it's okay to prune some, you should only try to remove the growing tips so as not to leave large wounds that may draw squash pests and diseases.

Your vegetables would certainly be edible.

I would clean up the plants and remove them from the garden if you don't want mystery plants again next year.

Is not considered resistant to squash vine borer.

This infestation could still attack this squash.

Here is an article that will help explain why your squash is bumpy and warty looking:

https://www.gardeningknowhow.com/edible/vegetables/squash/yellow-bumpy-squash.htm

Here is an extension article (PDF) that discusses why pumpkins do not set fruit:

https://bit.ly/1IY5a90

Happy gardening!

It can't happen. Squash and cucumbers crossing is like cats and dogs breeding with each other. Genetically impossible.

That being said, cucumbers and melons are actually genetically close enough to cross, so that may be an offspring of that kind of crossing. But the crossing would have been with the plant that grew the seed that you planted. Crossing does not affect the fruit of the plant that gets cross pollinated, it affects that seeds of the plant that gets cross pollinated.

Still, even this is unlikely. More likely is you either have an under pollinated cucumber that came out round because all of the seeds did not develop or you have a sport. A genetic mutation. Since there are some varieties of round cucumbers out there, this is very possible too.

The growing tip, new growth located in the tops of plants, can be pinched or snipped from the plant in order to produce a more compact growth habit or inhibit spreading.